产品货号：
Z35755
中文名称：
NME1抗体
英文名称：
Anti-NME1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NME1 Antibody |
| 指标别名 | AWD;GAAD;Granzyme A activated DNase;NB;NBS;NDK A;NDP kinase A;NDPK A;NDPKA;NME1;NM23;NM23-H1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | NME1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human NM23A Major role in the synthesis of nucleoside triphosphates other than ATP.Possesses nucleoside-diphosphate kinase,serine/threonine-specific protein kinase,geranyl and farnesyl pyrophosphate kinase,histidine protein kinase and 3'-5' exonuclease activities. |
| 实际分子量 | 17KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NME1(NME/NM23 nucleoside diphosphate kinase 1),also called non-metastatic cells 1,protein (NM23A) expressed in,NM23,NM23-H1,NDPKA,GAAD or AWD,is an enzyme that in humans is encoded by the NME1 gene.The promoters of the mouse and human NME1 genes,like those of other NME genes,contain several binding sites for AP2,NF1,Sp1,LEF1,and response elements to glucocorticoid receptors.The NME1 gene is mapped on 17q21.33.Immunofluorescence microscopy demonstrated colocalization of NME1 in nuclei of B cells expressing EBNA3C.Expression of EBNA3C reversed the ability of NME1 to inhibit migration of BL and breast carcinoma cells.NM23H1 bound SET and was released from inhibition by GZMA cleavage of SET.After GZMA loading or cytotoxic T lymphocyte attack,SET and NM23H1 translocated to the nucleus and SET was degraded,allowing NM23H1 to nick chromosomal DNA.Using a Drosophila model system,Dammai et al.(2003) showed that the Drosophila NME1 homolog,awd,regulates trachea cell motility by modulating FGFR levels through a dynamin -mediated pathway. |
| Uniprot ID | P15531 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：NME1抗体，NME1单抗，Anti-NME1 Antibody